NucleoCounter® NC-202™

Any culture - Any user - Any location

Automated cell counter

Chemometec NucleoCounter® NC-202™

Main features

  • Consistency between tools, users and sites
  • Eliminate human error with Via2-Cassette™.
  • Monitor production runs with the NEW DebrisIndex™.
  • Increased cell count range: No further dilutions
  • Scalable system with 21 CFR Part 11 / GMP-ready software
  • All the personal support of our dedicated experts
Chemo metec

Design and Usability

The NucleoCounter® NC-202™ automated cell counter is the third generation of our cassette-based instruments. With improved hardware and new easy-to-use NC-View™ software, we take cell counting accuracy, speed and data management to new levels.

Technology

The NucleoCounter® NC-202™ is the most accurate automated cell counter on the market: The combined operator-to-operator/instrument variation
between operators / between instruments
is typically 5 – 10%. We achieve superior performance thanks to high quality components that are stable over time and advanced factory calibrations.

Therefore, identical results are obtained with any cell sample, recorded by any user, anywhere in the world.

More features:

The new DebrisIndex™ is a measure of crop residue accumulation. These negatively affect the subsequent filtration and purification steps, so a direct measurement of the residues makes it easier to obtain better parameters in the development of the process.

The DebrisIndex™ can also be used as an additional readout of cell culture “health”. Together with data on standard biological parameters such as live and dead cells, cell diameter, aggregation, etc., the DebrisIndex™ provides an accurate picture of overall cell culture performance.

When correlated with the data for the production result, the DebrisIndex™ establishes the specifics of when to initiate the next step. The DebrisIndex™ can also increase with culture contamination e.g. by bacteria or fungi, which is an additional purity parameter.

CM graph 010520 V3 ml 768x433 1

NC-View™ software is compliant with 21 CFR Part 11/GMP guidelines and can be integrated into your clinical workflow. This allows a clean transfer of protocols involving the NucleoCounter® NC-202™ automated cell counter across departments and applications from R&D to QC.

Figure 2 3

We offer a simple to use workflow: Just load the sample, press RUN and get the data.

The unique Via2-Cassette™ combines sample aspiration, cell staining and counting chamber loading in one simple step. Insert the loaded Via2-Cassette™ into the NucleoCounter® NC-202™ and press RUN. The NC-View™ software will automatically acquire fluorescent images, identify the cells and present the data.

The standardized workflow ensures that handling interference is negligible for the highest data robustness.

The NucleoCounter® NC-202™ automated cell counter offers the best cell counting accuracy on the market, with a total linearity of up to 1×107 cells/ml. This facilitates laboratory work, reducing the need to dilute samples prior to measurements.

Workflow 301 Cell counting process 1 1024x292 1

The closed cell counting system, which uses self-contained disposable cassettes, helps the user to be protected and to be when handling samples. The absence of pipettes, the exposure to (toxic) reagents and minimal cleaning make the NucleoCounter® a safe choice. NucleoCounter® a safe choice.

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Chemometec NucleoCounter® NC-202™

Automated cell counter

Specifications table.

Loading volume App. 60 μl loaded into the Via2-Cassette™.
Analyzed volume 1.35 μl (volume-calibrated Via2-Cassette™)
Analysis time 30 seconds
Optimal range 5×104 to 1×107 cells/ml
Size 38 × 26 × 22 cm (W × H × D)
Weight 4.9 kg (10.8 lb)
Software NC-View™.
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