Cellular Toxicology

Cytotoxicity screening

Cytotoxicity screening

The detailed study of cell health with exceptional reproducibility is key to assessing cell vitality. Changes in, for example, cell cycle profile or apoptotic characteristics are essential to determine the impact of cytotoxicity.

Technology and usability

Studies on the impact of environmental and chemical compounds on living organisms are of enormous importance for:

  • Drug discovery
  • Chemical regulations
  • Understanding cell biology

Treatment of cells with toxic compounds leads to cell death by necrosis or apoptosis, so it is important to distinguish between the two. The study of cell toxicity requires rapid, reliable and detailed analysis.

NucleoCounter® instruments provide solution platforms ranging from accurate cell counting and viability determination to advanced cell analysis.

Specific applications:

  • Cytotoxicity research
  • Cytotoxicity: Determination of apoptosis and necrosis
  • Rapid cell cycle analysis
  • Monitoring of cell viability and GFP expression levels in cells

The NucleoCounter® NC-200™ is a highly accurate automated cell counter using state-of-the-art imaging cytometry. Counts cells in suspension, aggregated cells, CAR-T cells, stem cells and cells in microcarriers.

The NC-3000™ can perform cell counting and viability determination at high speed and includes plug-and-play analytical assays for mammalian, yeast and insect cells. The NC-3000™ can perform cell counting and viability determination at high speed and includes plug-and-play analytical assays for mammalian, yeast and insect cells.

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